The IRB is guided by the ethical principles applied to all research involving humans as participants, as outlined in the report of the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research, the “Ethical Principles and Guidelines for the Protection of Human Subjects of Research” (The Belmont Report). These principles are:
Beneficence—the benefits to the participant and importance of the knowledge to be gained outweigh the risks to the participant and merit a decision to allow the participant to accept these risks.
Autonomy—legally effective informed consent is obtained unless requirements for waiver of informed consent are met by appropriate methods.
Justice—selection of participants is equitable and representative of the group that will benefit from the research.
The Belmont Report was the first U.S. government publication to set rules for human subject research and is an essential reference work for IRB members. For more information on this report, please view this 9 minute video.
In addition, "Subpart A: Basic HHS Policy for Protection of Human Research Subjects," is the uniform set of regulations IRBs use to make decisions and recommendations.
HHS Policy for Protection of Human Subjects (45 CFR Part 46)
Columbia College Chicago Policy to Protect Human Subjects & Animals
Amended Policy for Use of Animals at Columbia College Chicago